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The web site api.cafevariome.org states the following, "Built-in Beacon functionality for Cafe Variome installations." I noticed that the webpage said " University of Leicester - Internet for DNABeacon article." They also said " UMCG CardioKit variants - Cafe Cardio. Nature Protocols HGV2014 Blog Post. A data discovery platform for sequence variant data. Clean, intuitive interface for complete control over data discovery and subsequent data sharing. Connecting disease consortia, diagnostic networks and 3rd parties various sharing scenarios. Installations can be hosted by Cafe Variome or installed locally." The meta header had mutation as the first optimized keyword. This keyword is followed by diagnostics and database which isn't as urgent as mutation.